Principal Scientist / Associate Director, Muscular Dystrophy and RNA Therapeutics Discovery

EPM Scientific

Currently partnering with a biotech at the forefront of innovation in the RNA Therapeutics space to hire a Principal Scientist/Associate Director to lead in preclinical studies for their best-in-class suite of therapeutics targeted at Muscular Dystrophy. This startup is exceptionally well-supported and positioned for monumental success, having already secured a major pharma collaboration for this program.

Reporting directly to the VP of Discovery, you will play a key role in evaluating lead compounds for efficacy, safety, and PK. A large portion of this role will involve developing novel in vitro assays to assess safety of these compounds as well as designing/overseeing in vivo studies through CROs.

Key Responsibilities:

  • Execute pharmacology and preclinical studies to assess efficacy and safety of lead candidates
  • Develop novel assays; particularly assays to assess safety, toxicity, and on/off target effects
  • Manage and oversee relationships with CROs and external partners
  • Excel in a highly collaborative startup environment


  • PhD with 6+ years industry experience
  • Expertise with Muscular Dystrophy Research required (i.e. DMD, FSHD, etc.)
  • Experience evaluating the efficacy, safety, and PK of RNA therapeutics or other modalities via a wide array of both in vivo and in vitro assays; proven expertise in novel assay development
  • Experience with nucleic acid therapeutic discovery would be a plus but not required

Full compensation package to include generous company equity and competitive benefits package. Relocation Assistance to the Greater-DC area available for non-local candidates

Washington DC, Washington DC, United States
Job Type
Employment Type
Full Time
Job Location
On Site
Valid Through
01 Nov 2023
Posted On
11 Sep 2023

Organisation Information

EPM Scientific

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