A post-doctoral fellow position is available for a highly motivated individual to join the Mohassel laboratory in the Department of Neurology at Johns Hopkins School of Medicine.
The Mohassel laboratory focuses on translational studies in genetic neuromuscular disorders. In particular, this position focuses on studies of disruption of regulation of sphingolipid biosynthesis as a cause of motor neuron disease. Several in vitro and in vivo model systems including patient cells, iPSCs and iPSC derived motor neurons, and mouse models of a monogenic form of motor neuron disease due to pathogenic variants in the SPTLC1 gene have been developed and will be used as part of this project. This project will also require the testing of several therapeutic candidates in vitro, and in vivo (mouse model), including small molecules, RNA-directed, and DNA-directed therapeutics. The post-doctoral fellow will receive close mentroship and guidance from the principal investigator and they will have access to numerous opportunities to enrich their training and career at a world class University. This role has the potential to provide opportunities for significant scientific productivity.
Candidates should hold a doctorate degree with extensive background in molecular biology, cell biology, genetics, biochemistry or a related field.
Candidates should be willing to work with murine models of disease, though specific training will be provided as needed.
Candidates with experience in culturing iPSCs are preferred.
Candidates with a record of research excellence demonstrated by publications will be favored.
Applicants from diverse backgrounds are strongly encouraged to apply.
Interested candidates should send their CV, a brief letter outline of their future research goals, and names and contact information for at least two references to:
Payam Mohassel, M.D.
Associate Professor of Neurology
Johns Hopkins School of Medicine